Gene information
Official symbol IL33
Official full name interleukin 33
Gene type protein-coding gene
Chromosome9p24.1
Alias symbolDVS27; DKFZp586H0523; NF-HEV; IL1F11
Previous symbolC9orf26
Gene familyInterleukins
Resources
Entrez Gene 90865
HGNC HGNC:16028
Ensembl ENSG00000137033
Vega OTTHUMG00000019516
UCSC uc064sap.1
GO terms: 26 records
GO Description Category LogP Number of genes Detail
GO:0001819 positive regulation of cytokine production GO Biological Processes -44.1872667 64 More
GO:0002694 regulation of leukocyte activation GO Biological Processes -32.0887020 60 More
GO:0002696 positive regulation of leukocyte activation GO Biological Processes -27.9249645 47 More
GO:0005125 cytokine activity GO Molecular Functions -54.7097150 57 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0019221 cytokine-mediated signaling pathway GO Biological Processes -27.5840932 43 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031349 positive regulation of defense response GO Biological Processes -32.1301903 71 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0032642 regulation of chemokine production GO Biological Processes -25.2850711 37 More
GO:0032675 regulation of interleukin-6 production GO Biological Processes -28.2553997 51 More
GO:0032680 regulation of tumor necrosis factor production GO Biological Processes -32.0729913 56 More
GO:0032755 positive regulation of interleukin-6 production GO Biological Processes -18.6559032 31 More
GO:0043032 positive regulation of macrophage activation GO Biological Processes -14.1432953 16 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050729 positive regulation of inflammatory response GO Biological Processes -38.1621935 57 More
GO:0050865 regulation of cell activation GO Biological Processes -40.6877761 71 More
GO:0050867 positive regulation of cell activation GO Biological Processes -31.2431659 51 More
GO:0070663 regulation of leukocyte proliferation GO Biological Processes -26.8242532 37 More
GO:0070664 negative regulation of leukocyte proliferation GO Biological Processes -3.96184640 13 More
GO:0071345 cellular response to cytokine stimulus GO Biological Processes -39.647808 70 More
GO:1903018 regulation of glycoprotein metabolic process GO Biological Processes -5.51204462 13 More
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -32.3948799 57 More
KEGG pathways: 3 records
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04217 Necroptosis KEGG Pathway -8.49909048 15 More
hsa05164 Influenza A KEGG Pathway -16.0885267 23 More
Related studies: 5 records
Molecular factor Omics type Application Objective MI type Reference
interleukin-33 proteomics death[prognosis (bad)] acute ST elevation myocardial infarction Dhillon OS et al. Int J Cardiol. 2013
interleukin-33 proteomics death[prognosis (bad)] acute ST elevation myocardial infarction Dhillon OS et al. Int J Cardiol. 2013
interleukin-33 proteomics good predictor adverse events[prognosis (bad)] acute myocardial infarction Zhang K et al. Chin Med J (Engl). 2013
interleukin-33 proteomics poor predictor major adverse cardiovascular events[prognosis (bad)] acute myocardial infarction Wang YP et al. J Cell Mol Med. 2017
interleukin-33 proteomics atorvastatin plus ticagrelor[treatment (pharmacotherapy)] ST elevation myocardial infarction Zhang L et al. J Int Med Res. 2020
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